Suplementos dietéticos y ejercicio físico en el síndrome de ovario poliquístico
DOI:
https://doi.org/10.56200/mried.v4i12.9284Palabras clave:
Ejercicio físico, Síndrome de ovario poliquístico, Suplementos dietéticosResumen
El síndrome de ovario poliquístico (SOP) es un trastorno endocrino-metabólico de múltiples factores que afecta de manera considerable la salud reproductiva, metabólica y psicológica de las mujeres en etapa reproductiva. Esta revisión narrativa estudió los efectos del consumo de suplementos dietéticos y la práctica de ejercicio físico en la prevención y/o tratamiento del SOP, haciendo énfasis en el manejo de sintomatología. La búsqueda abarcó estudios de repositorios electrónicos MEDLINE (PubMed), Registro Central Cochrane de Pruebas Controladas y Web of Science. Se escogieron 14 investigaciones desde 2014 hasta 2024, incluyen revisiones sistemáticas, metaanálisis, revisiones narrativas, guías clínicas y un ensayo clínico. Los principales resultados, el ejercicio constante potencia la sensibilidad a la insulina y regulación hormonal. Los suplementos tales como el inositol, omega-3, vitamina D y curcumina demostraron tener una posible eficacia para aliviar síntomas del SOP y mejorar el metabolismo de estas mujeres. Para concluir, la evidencia sugiere que modificaciones en el estilo de vida que incluyen ejercicio físico y algunos suplementos nutricionales pueden disminuir los síntomas y mejorar parámetros metabólicos y reproductivos, particularmente en mujeres con exceso de peso y resistencia a la insulina. Sin embargo, la diversidad metodológica requiere que se interpreten los hallazgos con prudencia.
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Abraham Gnanadass, S., Divakar Prabhu, Y., & Valsala Gopalakrishnan, A. (2021). Association of metabolic and inflammatory markers with polycystic ovarian syndrome (PCOS): An update. Archives of Gynecology and Obstetrics, 303(3), 631–643. https://doi.org/10.1007/s00404-020-05951-2 DOI: https://doi.org/10.1007/s00404-020-05951-2
Alesi, S., Ee, C., Moran, L. J., Rao, V., & Mousa, A. (2022). Nutritional Supplements and Complementary Therapies in Polycystic Ovary Syndrome. Advances in Nutrition, 13(4), 1243–1266. https://doi.org/10.1093/advances/nmab141 DOI: https://doi.org/10.1093/advances/nmab141
Arietaleanizbeaskoa, M. S., Sancho, A., Olazabal, I., Moreno, C., Gil, E., Garcia-Alvarez, A., Mendizabal, N., de la Fuente, I., Dominguez, S., Pablo, S., & Grandes, G. (2020). Effectiveness of physical exercise for people with chronic diseases: The EFIKRONIK study protocol for a hybrid, clinical and implementation randomized trial. BMC Family Practice, 21, 227. https://doi.org/10.1186/s12875-020-01298-4 DOI: https://doi.org/10.1186/s12875-020-01298-4
Ashkar, F., Eftekhari, M. H., Tanideh, N., Koohpeyma, F., Mokhtari, M., Irajie, C., & Iraji, A. (2020). Effect of hydroalcoholic extract of Berberis integerrima and resveratrol on ovarian morphology and biochemical parameters in Letrozole-induced polycystic ovary syndrome rat model: An experimental study. International Journal of Reproductive Biomedicine, 18(8), 637–650. https://doi.org/10.18502/ijrm.v13i8.7505 DOI: https://doi.org/10.18502/ijrm.v13i8.7505
Berger, M. M., Shenkin, A., Schweinlin, A., Amrein, K., Augsburger, M., Hans-Konrad Biesalski, Bischoff, S. C., Casaer, M. P., Kursat Gundogan, Lepp, H.-L., Man, Muscogiuri, G., Pietka, M., Pironi, L., Serge Rezzi, & Cuerda, C. (2022). ESPEN micronutrient guideline. Clinical Nutrition, 41(6), 1357–1424. https://doi.org/10.1016/j.clnu.2022.02.015 DOI: https://doi.org/10.1016/j.clnu.2022.02.015
Calcaterra, V., Verduci, E., Cena, H., Magenes, V. C., Todisco, C. F., Tenuta, E., Gregorio, C., De Giuseppe, R., Bosetti, A., Di Profio, E., & Zuccotti, G. (2021). Polycystic Ovary Syndrome in Insulin-Resistant Adolescents with Obesity: The Role of Nutrition Therapy and Food Supplements as a Strategy to Protect Fertility. Nutrients, 13(6), Article 6. https://doi.org/10.3390/nu13061848 DOI: https://doi.org/10.3390/nu13061848
Cheema, B. S., Vizza, L., & Swaraj, S. (2014). Progressive resistance training in polycystic ovary syndrome: Can pumping iron improve clinical outcomes? Sports Medicine (Auckland, N.Z.), 44(9), 1197–1207. https://doi.org/10.1007/s40279-014-0206-6 DOI: https://doi.org/10.1007/s40279-014-0206-6
Chen, W., & Pang, Y. (2021). Metabolic Syndrome and PCOS: Pathogenesis and the Role of Metabolites. Metabolites, 11(12), Article 12. https://doi.org/10.3390/metabo11120869 DOI: https://doi.org/10.3390/metabo11120869
Costello, M. F., Misso, M. L., Balen, A., Boyle, J., Devoto, L., Garad, R. M., Hart, R., Johnson, L., Jordan, C., Legro, R. S., Norman, R. J., Mocanu, E., Qiao, J., Rodgers, R. J., Rombauts, L., Tassone, E. C., Thangaratinam, S., Vanky, E., Teede, H. J., & International PCOS Network. (2019). Evidence summaries and recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome: Assessment and treatment of infertility. Human Reproduction Open, 2019(1), hoy021. https://doi.org/10.1093/hropen/hoy021 DOI: https://doi.org/10.1093/hropen/hoy021
De Araújo Medeiros Dias, D., Silva, I. L., & Jovita, M. C. (2022). Síndrome do Ovário Policístico e Vitamina D. Research Society And Development, 11(11), e521111131907. https://doi.org/10.33448/rsd-v11i11.31907 DOI: https://doi.org/10.33448/rsd-v11i11.31907
Dobbie, L. J., Pittam, B., Zhao, S. S., Alam, U., Hydes, T. J., Barber, T. M., & Cuthbertson, D. J. (2023). Childhood, adolescent, and adulthood adiposity are associated with risk of PCOS: A Mendelian randomization study with meta-analysis. Human Reproduction (Oxford, England), 38(6), 1168–1182. https://doi.org/10.1093/humrep/dead053 DOI: https://doi.org/10.1093/humrep/dead053
Fatima, K., Jamil, Z., Faheem, S., Adnan, A., Javaid, S. S., Naeem, H., Mohiuddin, N., Sajid, A., & Ochani, S. (2023). Effects of myo-inositol vs. metformin on hormonal and metabolic parameters in women with PCOS: A meta-analysis. Irish Journal of Medical Science, 192(6), 2801–2808. https://doi.org/10.1007/s11845-023-03388-5 DOI: https://doi.org/10.1007/s11845-023-03388-5
Febres Balestrini, F. (2016). Etiología del síndrome de ovario poliquístico. Revista de Obstetricia y Ginecología de Venezuela, 76, S5–S9.
García-Sáenz, M. R., Ferreira-Hermosillo, A., & Miry Lobaton-Ginsberg. (2022). Citocinas proinflamatorias en el síndrome de ovario poliquístico. Revista Médica Del Instituto Mexicano Del Seguro Social, 60(5), 569. https://doi.org/10396056/pdf/04435117-60-5-569
Greff, D., Juhász, A. E., Váncsa, S., Váradi, A., Sipos, Z., Szinte, J., Park, S., Hegyi, P., Nyirády, P., Ács, N., Várbíró, S., & Horváth, E. M. (2023). Inositol is an effective and safe treatment in polycystic ovary syndrome: A systematic review and meta-analysis of randomized controlled trials. Reproductive Biology and Endocrinology, 21(1), 10. https://doi.org/10.1186/s12958-023-01055-z DOI: https://doi.org/10.1186/s12958-023-01055-z
Gu, Y., Zhou, G., Zhou, F., Wu, Q., Ma, C., Zhang, Y., Ding, J., & Hua, K. (2022). Life Modifications and PCOS: Old Story But New Tales. Frontiers in Endocrinology, 13, 808898. https://doi.org/10.3389/fendo.2022.808898 DOI: https://doi.org/10.3389/fendo.2022.808898
Hafizi Moori, M., Nosratabadi, S., Yazdi, N., Kasraei, R., Abbasi Senjedary, Z., & Hatami, R. (2023). The Effect of Exercise on Inflammatory Markers in PCOS Women: A Systematic Review and Meta-Analysis of Randomized Trials. International Journal of Clinical Practice, 2023, 3924018. https://doi.org/10.1155/2023/3924018 DOI: https://doi.org/10.1155/2023/3924018
Kiani, A. K., Donato, K., Dhuli, K., Stuppia, L., & Bertelli, M. (2022). Dietary supplements for polycystic ovary syndrome. Journal of Preventive Medicine and Hygiene, 63(2S3), Article 2S3. https://doi.org/10.15167/2421-4248/jpmh2022.63.2S3.2762
Park, S. J., Kim, T.-H., & Oh, S. (2020). Immediate Effects of Tibialis Anterior and Calf Muscle Taping on Center of Pressure Excursion in Chronic Stroke Patients: A Cross-Over Study. International Journal of Environmental Research and Public Health, 17(11), 4109. https://doi.org/10.3390/ijerph17114109 DOI: https://doi.org/10.3390/ijerph17114109
Patten, R. K., Boyle, R. A., Moholdt, T., Kiel, I., Hopkins, W. G., Harrison, C. L., & Stepto, N. K. (2020). Exercise Interventions in Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis. Frontiers in Physiology, 11, 606. https://doi.org/10.3389/fphys.2020.00606 DOI: https://doi.org/10.3389/fphys.2020.00606
Petersen, A., & Pedersen, B. (2005). The anti-inflammatory effect of exercise. Journal of Applied Physiology, 98(4), 1154–1162. https://doi.org/10.1152/japplphysiol.00164.2004 DOI: https://doi.org/10.1152/japplphysiol.00164.2004
Sharma, P., Bhatia, K., Singh Kapoor, H., Kaur, B., & Khetarpal, P. (2023). Genetic variants of metabolism and inflammatory pathways, and PCOS risk -Systematic review, meta-analysis, and in-silico analysis. Gene, 888, 147796. https://doi.org/10.1016/j.gene.2023.147796 DOI: https://doi.org/10.1016/j.gene.2023.147796
Singh, J. R., Jain, A., Wadhwa, N., H.R., T., & Ahirwar, A. K. (2022). La resistencia a la insulina como factor etiológico en el síndrome del ovario poliquístico: un estudio de casos y controles. Advances in Laboratory Medicine / Avances En Medicina de Laboratorio, 3(2), 205–209. https://doi.org/10.1515/almed-2022-0050 DOI: https://doi.org/10.1515/almed-2022-0050
Stener-Victorin, E., Teede, H., Norman, R. J., Legro, R., Goodarzi, M. O., Dokras, A., Laven, J., Hoeger, K., & Piltonen, T. T. (2024). Polycystic ovary syndrome. Nature Reviews. Disease Primers, 10(1), 27. https://doi.org/10.1038/s41572-024-00511-3 DOI: https://doi.org/10.1038/s41572-024-00511-3
Stepto, N. K., Patten, R. K., Tassone, E. C., Misso, M. L., Brennan, L., Boyle, J., Boyle, R. A., Harrison, C. L., Hirschberg, A. L., Marsh, K., Moreno-Asso, A., Redman, L., Thondan, M., Wijeyaratne, C., Teede, H. J., & Moran, L. J. (2019). Exercise Recommendations for Women with Polycystic Ovary Syndrome: Is the Evidence Enough?. Sports medicine (Auckland, N.Z.), 49(8), 1143–1157. https://doi.org/10.1007/s40279-019-01133-6 DOI: https://doi.org/10.1007/s40279-019-01133-6
Stevens, S. L. (2021). Fat-Soluble Vitamins. Nursing Clinics of North America, 56(1), 33–45. https://doi.org/10.1016/j.cnur.2020.10.003 DOI: https://doi.org/10.1016/j.cnur.2020.10.003
Teede, H. J., Misso, M. L., Costello, M. F., Dokras, A., Laven, J., Moran, L., Piltonen, T., & Norman, Robert. J. (2018). Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome. Fertility and sterility, 110(3), 364–379. https://doi.org/10.1016/j.fertnstert.2018.05.004 DOI: https://doi.org/10.1111/cen.13795
Teede, H. J., Tay, C. T., Laven, J., Dokras, A., Moran, L. J., Piltonen, T. T., Costello, M. F., Boivin, J., M Redman, L., A Boyle, J., Norman, R. J., Mousa, A., Joham, A. E., & International PCOS Network. (2023). Recommendations from the 2023 International Evidence-based Guideline for the Assessment and Management of Polycystic Ovary Syndrome. Fertility and Sterility, 120(4), 767–793. https://doi.org/10.1016/j.fertnstert.2023.07.025 DOI: https://doi.org/10.1097/OGX.0000000000001233
Villanea, C. F. (2018). Síndrome de ovario poliquístico. Revista Médica Sinergia, 3(6), Article 6. https://doi.org/10.31434/rms.v3i6.130 DOI: https://doi.org/10.31434/rms.v3i6.130
Woodward, A., Klonizakis, M., & Broom, D. (2020). Exercise and Polycystic Ovary Syndrome. Advances in Experimental Medicine and Biology, 1228, 123–136. https://doi.org/10.1007/978-981-15-1792-1_8 DOI: https://doi.org/10.1007/978-981-15-1792-1_8
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Derechos de autor 2025 Stephanie-Marie Cruz-Pierard, Samuel-Olegario Iñiguez-Jiménez, Jonathan-Luis Cruz-Pierard

Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial-SinDerivadas 4.0.





































