Ejercicio multicomponente como estrategia para la prevención de fragilidad  en adultos mayores: revisión sistemática

Ronald Garces Quilambaqui; Iván Jaya Pineda

doi:10.56200/mentor.v5i15.12831

Authors

Ronald Garces Quilambaqui Universidad Técnica de Machala, Machala-Ecuador
Iván Jaya Pineda Universidad Técnica de Machala, Machala-Ecuador

DOI:

https://doi.org/10.56200/mentor.v5i15.12831

Keywords:

Multicomponent Exercise, Frailty, Older Adults, Systematic Review

Abstract

Frailty is one of the main geriatric syndromes associated with functional decline, falls, disability, and loss of independence in older adults. The objective was to synthesize the available evidence on the effectiveness of multicomponent exercise in preventing or reducing frailty in older adults. A systematic review was conducted in accordance with the 2020 Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, using searches in PubMed, Web of Science, and Scopus, with methodological assessment using the Physiotherapy Evidence Database scale for randomized studies, the Risk of Bias in Non-randomized Studies of Interventions tool for non-randomized studies, and the Grading of Recommendations Assessment Development and Evaluation system for the certainty of the evidence. Twenty studies were included that showed a generally favorable effect of multicomponent exercise on frailty, muscle strength, balance, gait, and functional ability; however, methodological quality was heterogeneous, and the certainty of the evidence was predominantly low. The results were interpreted by considering the identified risk of bias, inconsistency, indirectness, and imprecision; it was concluded that multicomponent exercise constitutes a promising strategy for managing frailty in older adults, although multicenter studies with standardized protocols are needed to strengthen the evidence.

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Author Biographies

Ronald Garces Quilambaqui, Universidad Técnica de Machala, Machala-Ecuador

Universidad Técnica de Machala, Machala-Ecuador

Iván Jaya Pineda, Universidad Técnica de Machala, Machala-Ecuador

Universidad Técnica de Machala, Machala-Ecuador

References

Alves, A., Martins, M., Pimenta, O., Almeida, J., Faria, E., Moreira, L., & Laredo, J. (2023). Effect of the Active Aging-in-Place–Rehabilitation Nursing Program: A Randomized Controlled Trial. Healthcare, 11(276), 1-16. https://doi.org/10.3390/healthcare11020276

Baltasar, I., Alcazar, J., Martín, S., Ara, I., Alegre, L., García, F., . . . Losa, J. (2024). Power oriented resistance training combined with high intensity interval training in pre frail and frail older people: comparison between traditional and cluster training set configurations on the force–velocity relationship, physical function and frailty. European Journal of Applied Physiology, 124(2), 623-632. https://doi.org/10.1007/s00421-023-05298-x

Cashin, A., & McAuley, J. (2020). Clinimetrics: Physiotherapy Evidence Database (PEDro) Scale. Journal of Physiotherapy, 66(1), 1. https://doi.org/10.1016/j.jphys.2019.08.005

Chen, B., Li, M., Zhao, H., Liao, R., Lu, J., Tu, J., . . . Wu, J. (2023). Effect of Multicomponent Intervention on Functional Decline in Chinese Older Adults: A Multicenter Randomized Clinical Trial. J Nutr Health Aging, 27(11), 1063-1075. https://doi.org/10.1007/s12603-023-2031-9

Chiu, T. Y., & Yu, H. W. (2022). Associations of multicomponent exercise and aspects of physical performance with frailty trajectory in older adults. BMC Geriatrics, 22(559), 1-10. https://doi.org/10.1186/s12877-022-03246-6

Clegg, A., Young, J., Iliffe, S., Olde, M., & Rockwood, K. (2013). Frailty in elderly people. The Lancet, 381(9869), 752-762. https://doi.org/10.1016/S0140-6736(12)62167-9

Dlima, S., Hall, A., Aminu, A., Akpan, A., Todd, C., & Vardy, E. (2024). Frailty: a global health challenge in need of local action. BMj Global Haelth, 9(8), 1-11. https://doi.org/10.1136/bmjgh-2024-015173

Dun, Y., Hu, P., Ripley, J., Zhou, N., Li, H., Zhang, W., . . . Liu, S. (2022). Effectiveness of a multicomponent exercise program to reverse pre-frailty in community-dwelling Chinese older adults:a randomised controlled trial. Age and ageing., 51(3), 1-11. https://doi.org/10.1093/ageing/afac026

Espinoza, E. (2025). PRISMA en la práctica: Guía y desafíos en la conducción de revisiones sistemáticas. Revista científica Sociedad & Tecnología, 8(52), 623-646. https://doi.org/10.51247/st.v8iS2.227

Furtado, G., Paes, M., Rodrigues, R., Lacerda, A., Uba, M., Vasconcelos, S., . . . Ferreira, J. (2025). Examining the impact of 28-week multicomponent and strength exercises on brain health, salivary stress, and mental well-being in frail older women: A controlled trial analysis. Physiology & Behavior, 15(249), 1-13. https://doi.org/10.1016/j.physbeh.2025.114868

Grubic, N., Johnston, A., Randhawa, V., Humphries, K., Rosella, L., & Maximova, K. (2025). Breaking Down Bias: A Methodological Primer on Identifying, Evaluating, and Mitigating Bias in Cardiovascular Research. Canadian Journal of Cardiology, 41(5), 996-1009. https://doi.org/10.1016/j.cjca.2024.12.022

Guamán, L., Machado, P., Herrera, A., & Valdiviezo, M. (2026). Estrategias comunitarias de enfermería para la promoción del bienestar integral del adulto mayor. Revista Finlay, 16(0), 1-8. https://doi.org/revfinlay.sld.cu/index.php/finlay/article/view/1618/2607

Imaoka, M., Hida, M., Nakamura, M., Sakai, K., Anzai, E., Ichise, T., . . . Hasegawa, Y. (2026). The effect of exercise and soy protein intake on physical frailty score improvement in community-dwelling elderly: a randomized controlled trial. Experimental Gerontology, 213, 1-8. https://doi.org/10.1016/j.exger.2025.112995

Izquierdo, M. (2019). Revista Nutrición Hospitalaria. Prescripción de ejercicio físico. El programa Vivifrail como modelo, 36(Ext.2), 50-56. https://doi.org/10.20960/nh.02680

Izquierdo, M., Merchant, R., Morley, J., Anker, S., Aprahamian, I., Arai, H., . . . Cadore, E. (2021). International Exercise Recommendations in Older Adults (ICFSR): Expert Consensus Guidelines. J Nutr Health Aging, 25(7), 824-853. https://doi.org/10.1007/s12603-021-1665-8

Ji, S., Yeon, J., Go, J., Lee, C., Soo, S., Jung, H.-W., . . . Jang, I.-Y. (2025). Effect of a combined exercise and nutrition program on sarcopenia in older adults: a randomised controlled trial in primary care. Australian Journal of Primary Health, 31, 1-8. https://doi.org/10.1071/PY24197

Jofré, E., Villalobos, Á., Cofré, C., Ferrari, G., & Gea, G. (2023). Multicomponent Training in Progressive Phases Improves Functional Capacity, Physical Capacity, Quality of Life, and Exercise Motivation in Community-Dwelling Older Adults: A Randomized Clinical Trial. International Journal Environmental Research Public Health, 20(3), 1-24. https://doi.org/10.3390/ijerph20032755

Kodama, A., Kume, Y., Otak, E., Fujimoto, M., Todo, H., Sasaki, N., . . . Ota, H. (2025). Effects of Pole- Assisted Multicomponent Exercise on Preventing Frailty Among Older Adults in Japan: A Quasi- Experimental Study. Psychogeriatrics, 25, 1-9. https://doi.org/10.1111/psyg.70067

Kusumowardani, A., Kuswardhani, T., Muliarta, M., & Ratna, L. (2025). Multicomponent Exercise Program Lowers Frailty Status and Improves IGF-1 Levels and Functional Performance in Frail Elderly. International Journal of Human Movement and Sports Sciences, 13(4), 699-707. https://doi.org/10.13189/saj.2025.130405

Maher , C., Sherrington, C., Herbert, R., Moseley, A., & Elkins, M. (2003). Reliability of the PEDro Scale for Rating Quality of Randomized Controlled Trials. Physical Therapy, 83(8), 713–721. https://doi.org/10.1093/ptj/83.8.713

Marcos, D., Hernandez, A., Cruces, S., Landa, J., Bonvini, M., Vicente, G., . . . Matheu, A. (2025). Resistance Exercise Intervention Restores Functional Capacity and Improves Frailty Biomarkers in Centenarians. Journal of Cachexia, Sarcopenia and Muscle, 16(70079), 1-6. https://doi.org/10.1002/jcsm.70079

Millan, F., Tarazona, F., Carretero, A., Olaso, G., Viña, J., & Gomez, M. (2022). Real-Life Outcomes of a Multicomponent Exercise Intervention in Community-Dwelling Frail Older Adults and Its Association with Nutritional-Related Factors. Nutrients, 14, 1-17. https://doi.org/10.3390/nu14235147

Moradell, A., Iguacel, I., Navarrete, D., Fernández, Á., González, M., Pérez, J., . . . Vicente, G. (2025). Effects of a multicomponent training and a detraining period on cognitive and functional performance of older adults at risk of frailty. Aging Clinical and Experimental Research, 37(117), 1-11. https://doi.org/10.1007/s40520-025-03011-w

Mulasso, A., Roppolo, R., Rainoldi, A., & Rabaglietti, E. (2022). Effects of a Multicomponent Exercise Program on Prevalence and Severity of the Frailty Syndrome in a Sample of Italian Community-Dwelling Older Adults. Healthcare, 10(911), 1-14. https://doi.org/10.3390/healthcare10050911

Ouzzani, M., Hammady, H., Fedorowicz, Z., & Elmagarmid , A. (2016). Rayyan—a web and mobile app for systematic reviews. BMC journals, 5(201), 1-10. https://doi.org/10.1186/s13643-016-0384-4

Page, M., McKenzie, J., Bossuyt, P., Boutron, I., Hoffmann, T., & Mulrow, C. (2021). The PRISMA 2020 statement: an updated guideline for reporting systematic reviews. BMJ, 1-9. https://doi.org/doi.org/10.1136/bmj.n71

Prasad, M. (2024). Introduction to the GRADE tool for rating certainty in evidence and recommendations. Clinical Epidemiology and Global Health, 25(101484), 1-5. https://doi.org/10.1016/j.cegh.2023.101484

Prommaban, A., Moonkayaow, S., Phinyo, P., Siviroj, P., Sirikul, W., & Lerttrakarnnon, P. (2024). The Effect of Exercise Program Interventions on Frailty, Clinical Outcomes, and Biomarkers in Older Adults: A Systematic Review. Journal Clinical Medicine, 13(21), 1-19. https://doi.org/10.3390/jcm13216570

Sanchéz, J., De Souto, P., Antón, I., Débora, M., & Casas, Á. (2022). Effects of a 12-week Vivifrail exercise program on intrinsic capacity among frail cognitively impaired community-dwelling older adults: secondary analysis of a multicentre randomised clinical trial. Age and Ageing, 51, 1-10. https://doi.org/10.1093/ageing/afac303

Sánchez, M., Pedreño , M., Ponce, A., & Navarro, F. (2023). Y, al principio, fue la pregunta de investigación … Los formatos PICO, PECO, SPIDER y FINER. Espiral. Cuadernos del Profesorado, 16(32), 126-136. https://doi.org/10.25115/ecp.v16i32.9102

Sandoval, M., Parrilla, E., & Padilla, L. (2023). Ejercicio multicomponente en el adulto mayor y su efecto en el síndrome de fragilidad. Alerta, 6(2), 142-148. https://doi.org/10.5377/alerta.v6i2.15613

Savvakis, I., Patelarou, A., Mechili, E., Stratidaki, E., Patelarou, E., & Giakoumidakis, K. (2025). Targeted Physical Function Exercises for Frailty and Falls Management in Pre-Frail Community-Dwelling Older Adults: ARandomized Controlled Trial. Healthcare, 13(2486), 1-15. https://doi.org/10.3390/healthcare13192486

Sherrington, C., Fairhall, N., Wallbank, G., Tiedemann, A., Michaleff, Z., Howard, K., . . . Lamb, S. (2020). Exercise for preventing falls in older people living in the community: an abridged Cochrane systematic review. British Journal of Sports Medicine, 54, 885-891. https://doi.org/10.1136/bjsports-2019-101512

Tan, L., Chan, Y., Seetharaman, S., Denishkrshna, A., Au, L., Kwek, S., . . . Merchant, R. (2023). Impact of Exercise and Cognitive Stimulation Therapy on Physical Function, Cognition and Muscle Mass in Pre-Frail Older Adults in the Primary Care Setting: A Cluster Randomized Controlled Trial. J Nutricion Healt Again, 27(6), 438-447. https://doi.org/10.1007/s12603-023-1928-7

Tay, L., Tay, E., Mah, S., Latib, A., & Ng, Y. (2022). Intrinsic capacity rather than intervention exposure influences reversal to robustness among prefrail community dwelling older adults: A non randomized controlled study of a multidomain exercise and nutrition intervention. Frontiers in Medicine, 9, 1-11. https://doi.org/10.3389/fmed.2022.971497

Tou, N., Goh, S., Harding, S., Tsao, M., Ng, T., & We, S.-L. (2024). Effectiveness of community-based Baduanjin exercise intervention for older adults with varying frailty status: a randomized controlled trial. European Review of Aging and Physical Activity, 21(28), 1-11. https://doi.org/10.1186/s11556-024-00363-6

Wang, Z., Meng, D., He, S., Guo, H., Tian, Z., Wei, M., . . . Wang, Z. (2022). The Effectiveness of a Hybrid Exercise Program on the Physical Fitness of Frail Elderly. Research Public Health, 19, 1-15. https://doi.org/10.3390/ijerph191711063